Augmentin 1G BD Tablets

Medicine Name: Augmentin 1000mg BD Tablets
✅ Augmentin Tablet Specification
Requires Prescription: Yes
Generics: Amoxicillin, Clavulanic Acid
Used For: Bacterial Infections
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⚙️ How It Works
•    Amoxicillin: A beta-lactam antibiotic that inhibits bacterial cell wall synthesis.
•    Clavulanic Acid: A beta-lactamase inhibitor that extends amoxicillin’s spectrum by overcoming bacterial resistance.
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💊 Usage and Safety
Dosage
•    Based on infection severity and patient profile (e.g., renal function).
•    Contains a fixed-dose combination of Amoxicillin + Clavulanic Acid (e.g., 500 mg/125 mg).

Side Effects
•    Common: Nausea, vomiting, diarrhoea, indigestion, headache, dizziness
•    Infectious: Mucocutaneous candidiasis
•    Hematologic: Reversible leucopenia, neutropenia, thrombocytopenia
•    Allergic: Angioneurotic oedema, anaphylaxis, serum sickness-like syndrome, hypersensitivity vasculitis
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🔄 Drug Interactions
•    Mycophenolate mofetil: Reduced plasma levels
•    Probenecid: Increases amoxicillin levels
•    Oral contraceptives: Reduced effectiveness
•    Warfarin/Acenocoumarol: May increase bleeding—monitor INR
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🎯 Indication
•    Broad-spectrum treatment of common bacterial infections, including:
o    Respiratory tract infections
o    Urinary tract infections
o    Skin/soft tissue infections
o    Dental infections
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🚫 When Not to Use
•    Hypersensitivity to penicillin’s, cephalosporins, or any beta-lactam antibiotics
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⚠️ Precautions
•    Take thorough allergy history (especially penicillin/cephalosporin) before prescribing
•    Use with caution in hepatic dysfunction or renal impairment
•    Monitor blood counts during prolonged therapy
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🚨 Warnings
1.    Risk of severe hypersensitivity (anaphylaxis, severe skin reactions)
2.    Prolonged use may lead to superinfections (e.g., fungal overgrowth)
3.    Dose adjustment needed in renal impairment
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🤰 Pregnancy Category
•    Use only if clearly needed—consult physician
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📦 Storage
Required: Yes
•    Store at room temperature, protected from light and heat