Augmentin 375MG Tablets

Medicine Name: Augmentin 375mg Tablets
✅ Augmentin Tablet Specification
Requires Prescription: Yes
Generics: Amoxicillin, Clavulanic Acid
Used For: Bacterial Infection
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⚙️ How It Works
•    Amoxicillin: A penicillin-type antibiotic that inhibits bacterial cell wall synthesis.
•    Clavulanic Acid: A beta-lactamase inhibitor that protects amoxicillin from degradation by resistant bacteria.
•    Combined Effect: Broadens antibacterial coverage to include beta-lactamase-producing organisms.
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💊 Usage and Safety
Dosage
•    Depends on the type and severity of infection; follow physician’s instructions.
•    Contains Amoxicillin + Clavulanic Acid in varying strengths (e.g., 500mg/125mg).
Side Effects
•    Common: Diarrhoea, nausea, vomiting, indigestion, dizziness, headache
•    Infectious: Mucocutaneous candidiasis
•    Blood-related: Reversible leucopenia (incl. neutropenia), thrombocytopenia
•    Allergic/Immune: Angioneurotic oedema, anaphylaxis, serum sickness-like syndrome, hypersensitivity vasculitis
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🔁 Drug Interactions
•    Mycophenolate mofetil: Reduced effectiveness
•    Probenecid: Increases blood levels of amoxicillin
•    Oral contraceptives: May reduce contraceptive effectiveness
•    Acenocoumarol/Warfarin: Increased bleeding risk—monitor INR
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🎯 Indication
Used to treat a wide range of bacterial infections, such as:
•    Respiratory tract infections
•    Urinary tract infections
•    Skin and soft tissue infections
•    Dental infections
•    Otitis media, sinusitis
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🚫 When Not to Use
Do not use Augmentin if:
•    You are allergic to penicillins, cephalosporins, or any beta-lactam antibiotic
•    You have had severe allergic reactions to antibiotics in the past
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⚠️ Precautions
•    Screen for history of penicillin or cephalosporin allergy
•    Monitor kidney and liver function in long-term use
•    Adjust dose in renal impairment
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🚨 Warnings
1.    Serious Allergic Reactions: Risk of anaphylaxis or severe skin reactions (e.g., SJS) in sensitive individuals
2.    Overuse: May lead to overgrowth of non-susceptible organisms like fungi
3.    Renal Impairment: Dose must be adjusted to avoid drug accumulation
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👶 Pregnancy Category
•    Consult your doctor before use during pregnancy or breastfeeding
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📦 Storage
Required: Yes
Store at room temperature, protected from light and heat.