Augmentin BD 35ml Suspension 457mg/5ml

Requires Prescription: Yes
Generics: Amoxicillin, Clavulanic Acid
Used For: Bacterial Infections
⚙️ How It Works
 Amoxicillin: A beta-lactam antibiotic that inhibits bacterial cell wall synthesis.
 Clavulanic Acid: A beta-lactamase inhibitor that prevents bacterial resistance by
inhibiting enzymes that degrade amoxicillin.
 This combination broadens the antimicrobial spectrum, making it effective against
resistant strains.
💊 Usage and Safety
Dosage
 Contains Amoxicillin + Clavulanic Acid in a BD (twice-daily) formulation.
 Dosing depends on the severity of the infection, age, weight, and renal function.
Side Effects
 Gastrointestinal: Nausea, vomiting, diarrhoea, indigestion
 Hematologic: Reversible leucopenia (incl. neutropenia), thrombocytopenia
 Allergic: Angioneurotic oedema, anaphylaxis, hypersensitivity vasculitis, serum
sickness-like syndrome
 Neurological: Dizziness, headache
 Fungal: Mucocutaneous candidiasis (yeast overgrowth)
🔄 Drug Interactions
 Probenecid: Increases amoxicillin levels
 Mycophenolate mofetil: Reduced plasma levels
 Warfarin / Acenocoumarol: Potential for increased bleeding—monitor INR
 Oral contraceptives: Reduced effectiveness
 Allopurinol: May increase risk of rash
🎯 Indication
 Effective for treatment of infections caused by susceptible bacteria, such as:
o Respiratory tract infections
o Urinary tract infections
o Skin and soft tissue infections
o Dental abscesses
🚫 When Not to Use
 Known hypersensitivity to penicillins, cephalosporins, or other beta-lactam antibiotics
 History of liver dysfunction or jaundice associated with previous use of the drug
⚠️ Precautions
 Conduct allergy history before starting treatment
 Use with caution in renal or hepatic impairment
 Regular monitoring may be required in long-term therapy

🚨 Warnings
1. Hypersensitivity Reactions: Life-threatening allergic reactions (e.g., anaphylaxis, SJS)
can occur.
2. Overgrowth of Non-Susceptible Organisms: Fungal or resistant bacterial overgrowth
with prolonged use.
3. Renal Impairment: Dose adjustment required—monitor kidney function.
🤰 Pregnancy Category
 Use only under medical supervision. Not known to be harmful but always consult your
physician.
📦 Storage
Required: Yes
 Store at room temperature, away from direct light and heat