Bamifix Tablets 600mg

Bamifix Tablets Specification Sheet

Requires Prescription: ✅ Yes

Generics

• Bamifylline

Used For

• Asthma
• Pulmonary diseases with a bronchospastic component

How It Works

Bamifylline is a methylxanthine derivative, chemically distinct from theophylline due to its side chains at positions 7 and 8.

• It exerts a bronchospasmolytic effect by relaxing bronchial smooth muscles.
• It also inhibits the action of bronchoconstrictive mediators, improving airflow and easing breathing in asthmatic patients.

Dosage

• Active Ingredient: Bamifylline
• Dosage is based on physician recommendation, typically adjusted based on patient response and condition severity.

Side Effects

Occasional:

• Headache
• Gastric discomfort (gastralgia)

Overdose-related:

• Nausea
• Mild distal tremors (resolves with dose reduction)

Allergic Reactions:

• Urticaria
• Rash
• Itching
• Dermatitis

Drug Interactions

Though no direct interactions with bamifylline are well-established, consider interactions known for theophylline:

Can Increase Serum Levels:

• Erythromycin, lincomycin, clindamycin
• Allopurinol, cimetidine
• Flu vaccine
• Propranolol

Can Decrease Serum Levels:

• Phenytoin, other anticonvulsants
• Cigarette smoking

Avoid Concomitant Use With:

• Other xanthine derivatives
• Ephedrine or other sympathomimetic bronchodilators (use with caution)

Indication

• Bronchial asthma
• Pulmonary conditions with bronchospasm, including chronic obstructive pulmonary disease (COPD)

When Not to Use

• Acute myocardial infarction
• Known hypersensitivity to bamifylline or xanthine derivatives
• Children, especially neonates or infants
• Severe heart failure
• Severe hypertension
• Liver or kidney insufficiency
• Peptic ulcer
• Hyperthyroidism

Precautions

• Not recommended in:
• Infants and young children
• Severe cardiovascular conditions
• Liver or kidney dysfunction
• Peptic ulcers
• Thyroid disorders

Warnings

Warning 1:
Not for pediatric use, especially in neonates or young children.

Warning 2:
Although animal studies show no reproductive toxicity, avoid use in the first trimester of pregnancy unless absolutely necessary.

Warning 3:
Avoid use in late pregnancy and during lactation as a precaution, despite no known neonatal toxicity.

Pregnancy Category

• Use with caution. Always consult your physician.

Storage

✅ Yes — Store at room temperature, away from direct light and heat.