Calamox 90ml Suspension 156.25mg/5ml

1. Prescription Status
Requires Prescription: ✅ Yes
2. Generic Name
 Amoxicillin
 Clavulanic Acid
3. Therapeutic Use
Calamox 90 mL is used for the treatment of bacterial infections, including those caused by
beta-lactamase–producing organisms. Common indications include:
 Respiratory tract infections
 Otitis media
 Sinusitis
 Urinary tract infections
 Skin and soft tissue infections
4. Mechanism of Action
 Amoxicillin: A penicillin-type antibiotic that inhibits bacterial cell wall synthesis,
leading to cell death.
 Clavulanic Acid: A beta-lactamase inhibitor that prevents the breakdown of
amoxicillin by resistant bacteria, thus enhancing its effectiveness.
5. Dosage
Contains a combination of Amoxicillin and Clavulanic Acid in oral suspension form.
 Dosage is based on body weight, age, infection severity, and renal function.
 Administer as prescribed by a physician. Shake well before use.
6. Side Effects
Common:
 Diarrhea
 Nausea, vomiting
 Indigestion
 Dizziness, headache
Less Common/Serious:
 Mucocutaneous candidiasis
 Reversible leukopenia, neutropenia, thrombocytopenia
 Hypersensitivity reactions such as:
o Angioneurotic oedema
o Anaphylaxis
o Serum sickness-like syndrome
o Hypersensitivity vasculitis
7. Drug Interactions
Use caution when co-administered with:
 Mycophenolate mofetil (reduced efficacy)
 Probenecid (increases amoxicillin concentration)
 Oral contraceptives (possible reduced effectiveness)
 Acenocoumarol or warfarin (increased bleeding risk)
8. Contraindications (When Not to Use)
 Known hypersensitivity to penicillins, cephalosporins, or any beta-lactam antibiotics.
9. Precautions
 A complete allergy history must be taken before therapy, especially regarding previous
reactions to penicillins or cephalosporins.
10. Warnings
1. Severe hypersensitivity reactions, including anaphylaxis, have occurred in penicillinallergic patients.
2. Prolonged use can lead to overgrowth of non-susceptible organisms.
3. In renal impairment, dose adjustment is essential to avoid accumulation and toxicity.
11. Pregnancy and Lactation
 Always consult a physician before use during pregnancy or breastfeeding.
12. Storage
✅ Yes
 Store at room temperature
 Keep away from direct light and heat
 Once reconstituted, refrigerate and use within the recommended period as per packaging
(typically 7–10 days)