Cefiget Capsules 400mg

1. Basic Information
 Requires Prescription: ✅ Yes
 Generic Name: Cefixime
 Used For: Treatment of Bacterial Infections
2. How It Works
Cefixime is a third-generation cephalosporin antibiotic.
 It works by binding to penicillin-binding proteins (PBPs) inside the bacterial cell wall.
 This inhibits the final stage of bacterial cell wall synthesis, causing cell lysis and death.
3. Indications
Cefixime is indicated for infections caused by susceptible microorganisms, including:
 Uncomplicated urinary tract infections (UTIs)
 Otitis media
 Pharyngitis and tonsillitis
 Acute bronchitis and acute exacerbations of chronic bronchitis
 Uncomplicated gonorrhea (cervical or urethral)
4. Dosage
 Generic Component: Cefixime
 Dosage to be determined by a physician based on infection severity and patient profile
5. Side Effects
 Common:
o Diarrhea (discontinue if severe)
o Nausea, vomiting
o Abdominal pain, dyspepsia
o Headache, dizziness
o Changes in stool color
 Less Common to Rare:
o Seizures (especially in renal impairment)
o Elevated liver enzymes, alkaline phosphatase, and serum amylase
o Transient jaundice
6. Drug Interactions
 Anticoagulants (e.g., warfarin) – ↑ bleeding risk
 Carbamazepine – ↑ serum levels
 Probenecid – ↓ renal clearance of cefixime
7. Contraindications (When Not to Use)
 Hypersensitivity to Cefixime or any cephalosporin antibiotic
 Known allergy to penicillin or other beta-lactams (cross-sensitivity risk)
8. Precautions
 Use cautiously in penicillin-sensitive patients due to potential cross-reactivity
 Monitor liver and kidney function during prolonged therapy
 Adjust dose in renal impairment
9. Warnings
Warning 1:
Use with caution in patients with severely impaired renal function.
Warning 2:
Broad-spectrum antibiotics, including cefixime, may disrupt gut flora and lead to Clostridium
difficile overgrowth (risk of pseudomembranous colitis).
Warning 3:
Caution is advised in patients with a history of gastrointestinal disease, especially colitis.
10. Additional Information
 Pregnancy Category:
Always consult your physician before use
 Storage: ✅ Yes
Store at room temperature, away from direct light and heat