Diovan Tablets 160MG

Medicine Name: Diovan Tablets 160mg

📄 Diovan Tablets – Product Specification
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Requires Prescription:
✅ Yes
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Generic Name:
Valsartan
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Used For:
•    Hypertension (high blood pressure)
•    Heart failure (NYHA class II–IV)
•    Post-myocardial infarction (to improve survival in patients with left ventricular dysfunction)
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How It Works:
Valsartan is an angiotensin II receptor blocker (ARB). It works by:
•    Blocking the binding of angiotensin II to the AT1 receptor in vascular smooth muscle and adrenal gland
•    Reducing vasoconstriction and aldosterone secretion
•    The action is independent of how angiotensin II is synthesized
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Usage and Safety
Dosage:
•    Valsartan (dose as prescribed by a physician based on condition and patient profile)
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Side Effects:
Common:
•    Viral infections
•    Neutropenia
•    Hyperkalemia
•    Dizziness, vertigo, postural hypotension
•    Hypotension
•    Renal impairment or failure
Uncommon:
•    URTI, pharyngitis, sinusitis
•    Insomnia, decreased libido
•    Syncope
•    Cardiac failure
•    Cough
•    GI upset: diarrhea, abdominal pain
•    Fatigue, asthenia
•    Back pain, headache, edema
Rare:
•    Dizziness (isolated report)
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Drug Interactions:
Use caution or avoid with:
•    Lithium
•    NSAIDs (including COX-2 inhibitors and high-dose aspirin)
•    Rifampin, ciclosporin, ritonavir (affect drug transporters)
•    Aliskiren (in diabetics or renally impaired patients)
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Indications:
•    Treatment of Hypertension
•    Management of Heart Failure (Class II–IV)
•    Improving survival post-myocardial infarction in patients with LV dysfunction
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When Not to Use:
Contraindicated in:
•    Hypersensitivity to valsartan or any excipients
•    Severe hepatic impairment, biliary cirrhosis, cholestasis
•    Pregnancy (2nd and 3rd trimesters)
•    Concomitant use with aliskiren in patients with:
o    Diabetes
o    Renal impairment (GFR < 60 mL/min/1.73 m²)
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Precautions:
•    Not effective in patients with primary hyperaldosteronism
•    Use cautiously in hepatic impairment (without cholestasis)
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Warnings:
🔴 Warning 1:
Avoid potassium-sparing diuretics, potassium supplements, or potassium-rich salt substitutes. Monitor serum potassium levels regularly.
🔴 Warning 2:
In patients with bilateral renal artery stenosis or a single kidney, valsartan may affect renal function. Monitor serum creatinine and urea.
🔴 Warning 3:
Use caution in mild to moderate liver disease; dose adjustment may be required.
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Pregnancy Category:
⚠️ Always consult your physician before using this medicine, especially during pregnancy.
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Storage:
✅ Yes – Store at room temperature, away from direct sunlight and heat