Requires prescription: Yes
Generic: Metronidazole
Used for: Treatment and prevention of bacterial infections
How it works: Kills bacteria and parasites by disrupting their DNA, preventing growth and
reproduction
Dosage:
Metronidazole (to be taken as prescribed by a healthcare professional)
Side effects may include:
Fits (convulsions), confusion, hallucinations, blurred or double vision, changes in colour vision,
eye pain, tinnitus, hearing problems, skin rash, flushing, itching, headache, darkened urine,
diarrhoea, drowsiness, dizziness, muscle or joint pain, numbness or tingling in arms or legs,
unpleasant taste in the mouth, dry mouth, furred tongue, nausea, vomiting, upset stomach,
stomach pain, loss of appetite, anorexia, depression, and fever
Drug interactions:
Warfarin, Lithium, Disulfiram, Phenobarbital, Phenytoin, Cyclosporin, 5-Fluorouracil, Busulfan
Indication:
Used to treat and prevent severe infections caused by anaerobic bacteria, including species such
as Bacteroides, anaerobic Streptococci, Fusobacteria, and Clostridia
When not to use:
Do not use if allergic to metronidazole or any of its ingredients. Signs of an allergic reaction
include rash, difficulty breathing or swallowing, and swelling of lips, face, throat, or tongue
Precaution:
In patients with Cockayne syndrome, liver function should be monitored closely during and after
treatment with metronidazole
Cases of severe liver toxicity and acute liver failure, including fatalities, have been reported in
patients with Cockayne syndrome taking metronidazole. Discontinue use and seek medical
attention if symptoms such as abdominal pain, nausea, vomiting, jaundice, fatigue, fever, dark
urine, pale stools, or itching appear. Rare but serious skin reactions such as Stevens-Johnson
Syndrome, Toxic Epidermal Necrolysis, and Acute Generalised Exanthematous Pustulosis have
also been reported
Pregnancy:
Always consult a physician before using any medication during pregnancy
Storage:
Store at room temperature, away from direct light and heat
