Zeegap Capsules Specification
Requires Prescription
Yes
Generics
Pregabalin
Used For
Neuropathic Pain
How it Works
Pregabalin reduces neuronal calcium currents by binding to the alpha-2-delta subunit of
voltage-gated calcium channels in CNS tissues. This action likely contributes to its effects on
neuropathic pain, anxiety, and other pain syndromes.
Usage and Safety
Dosage
Pregabalin (as prescribed)
Side Effects
Very common:
Dizziness, drowsiness, somnolence
Common:
Increased appetite, euphoric mood, confusion, irritability, decreased libido,
disorientation, insomnia, ataxia, abnormal coordination, tremor, dysarthria, memory
impairment, attention disturbance, paraesthesia, sedation, balance disorder, lethargy,
headache, blurred vision, diplopia, vertigo, vomiting, dry mouth, constipation, flatulence,
erectile dysfunction, abnormal gait, feeling drunk, fatigue, peripheral oedema, oedema,
weight gain
Uncommon:
Nasopharyngitis, anorexia, hypoglycemia, hallucination, panic attack, restlessness,
agitation, depression, depressed mood, mood swings, depersonalisation, word finding
difficulty, abnormal dreams, increased libido, anorgasmia, apathy, syncope, stupor,
myoclonus, psychomotor hyperactivity
Drug Interactions
CNS depressants (opiates, benzodiazepines)
Ethanol
Lorazepam
Oxycodone
Indications
Neuropathic pain from diabetic peripheral neuropathy
Postherpetic neuralgia
Pain due to spinal cord injury
Adjunctive therapy for partial seizures (with or without secondary generalization)
Generalized Anxiety Disorder (GAD) in adults
Fibromyalgia syndrome (FMS)
When Not to Use
Known hypersensitivity to pregabalin or any ingredients
Patients with rare hereditary problems such as galactose intolerance, Lapp lactase
deficiency, or glucose-galactose malabsorption
Precautions
Pregabalin should be withdrawn gradually over at least 1 week to minimize seizure risk in
patients with seizure disorders.
Warnings
1. Discontinue immediately if symptoms of angioedema (facial, perioral, or upper airway
swelling) occur.
2. Weight gain may occur, especially in diabetics who might need to adjust hypoglycemic
meds.
3. May cause dizziness and somnolence; caution advised when driving or operating
machinery, especially in elderly patients.
Additional Information
Pregnancy Category: Consult your physician before use.
Storage
Yes — Store at room temperature, away from direct light and heat.
